In goal is talismanic Spanish international and long-serving United keeper David De Gea. While not as overpowered as in previous titles, De Gea still boasts 89 reflexes and 86 diving, so can pull off some remarkable instinctive saves. Comfortably the strongest goalkeeping option in the United squad on FC 25 Coins. De Gea should come up clutch when it really counts.
A tough choice at left-back, as Luke Shaw is unlucky to miss out here. The Englishman is more than capable, and much comes down to personal preference. However, Alex Telles has phenomenal all-around stats and just plays superbly in-game. His pace, physicality and balanced feel make him a great pick, who can contribute in both attack and defense, while Shaw is a solid option to bring off the bench later in the match.
In central defense is big-name signing Raphael Varane. The Frenchman was brought into the United team to sure up their back line, and while things haven‘t gone so smoothly in the real world, on FC 25 he does exactly that.
Strong aerially, quick to cover back, and with great tackling ability, he is among the best defenders in FC 25. With 82 pace, 87 defending and 82 physical stats, Varane is an absolute rock at the back and deserving of his place in the heart of the defense.
Partnering with Varane is Eric Bailly. Despite a lower rating than real-world United captain Harry Maguire, Bailly has far better pace than the Englishman, and his 84 jumping, 85 strength and 85 aggression make him a beast at the back. Bailly can win headers, jostle attackers off the ball and dominate physically while having the pace and athleticism to recover if caught out of position.
Completing the back-four is Aaron Wan-Bissaka. What the formal Crystal Palace defender lacks in attacking output, he makes up for by being superb defensively. 85 pace allows him to hunt down opposing wingers, while his physical stats give him the cheap FIFA Coins ball-winning ability of most centre backs.